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Rotary bur vs piezo knife: which heals tooth bone better?

NCT ID NCT07197658

Disease control Sponsor: National and Kapodistrian University of Athens Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 17, 2026 · Updated 3 times

Summary

This study compares two ways to remove infection at the tip of a tooth root: using a rotary bur (a small drill) or a piezoelectric unit (a vibrating tool). 124 adults with root infections will have surgery and then be followed for 12 months to see which method leads to better bone healing. The goal is to find out if one technique helps the bone reform more completely.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
endodontic microsurgery (rotary bur or piezoelectric unit)
What this could lead to
If one method proves better, it could guide dentists to choose the technique that leads to faster or more complete bone healing after root surgery.
What could go wrong
This is a small, early-stage study (124 people) comparing surgical tools, not testing a new drug or cure. Results may not apply to all patients or guarantee better outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

124 people

The number who actually took part.

Started

Apr 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years and older consenting to the surgical procedure as well as agreeing to preoperative, postoperative and at least one follow-up CBCT evaluation after 12 months * Noncontributory medical history (American Society of Anesthesiologists class I and II) * A history of previous endodontic treatment with radiographic presence of apical periodontitis * A true endodontic lesion: microsurgical classification A, B, or C according to Kim and Kratchman, 2006. * Lesion size 10 mm or smaller in diameter measured on preoperative CBCT * Coronal restoration should be present at the time of follow up examination. Exclusion Criteria: * Nonconsenting patients and patients younger than 18 years of age * Medical history with American Society of Anesthesiologists class III to V * Insufficient coronal restoration * Nonrestorability or traumatized teeth * Teeth with microsurgical classification D, E, or F according to Kim and Kratchman, 2006. * Mobility I or higher * Radiographic presence of nonapical root resorption * Teeth with a vertical root fracture or coronal/ midroot perforation * Lesion size larger than 10 mm in diameter measured on preoperative CBCT * Use of bone graft material for regeneration

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Conditions

The condition(s) this trial relates to.

periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endodontic microsurgery Osteotomy Periapical periodontitis

Contacts and locations

Locations

  • Private Dental Office

    Athens, Attica, 11528, Greece

  • Spyros Floratos Private Dental Office

    Athens, Attica, 11528, Greece

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