Brain zaps to kick the habit: TMS trial targets smokers with mental health struggles

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patient Participants: The patient participant must meet all the inclusion criteria to be eligible for this study: 1. Able to provide informed consent. 2. Age 18-70. 3. Self-reported daily tobacco cigarette consumption. 4. Meet DSM-5 criteria for a psychiatric disorder that includes one of the following: mood disorders (e.g. major depressive disorder, bipolar disorder), anxiety disorders (e.g. panic disorder, social anxiety disorder), psychotic disorders (e.g. schizophrenia), posttraumatic stress disorder, obsessive compulsive disorders, or other substance use disorders (e.g. alcohol use disorder) as determined by the Structured Clinical Interview for DSM-5 Disorders, Research Version (SCID-5 RV). 5. Interested in using either Repetitive Transcranial Magnetic Stimulation (rTMS) or nicotine replacement therapy as a smoking cessation treatment. 6. Intending on quitting smoking within the next 30 days. Exclusion Criteria: Patient Participants: 1. Contraindication to rTMS according to the TMS Adult Safety Screen (TASS) and PI review. 2. Have any intracranial implant (e.g., aneurysm clips) or any other metal object within or near the head, excluding the mouth, that cannot be safely removed. 3. Pregnant or intending to be pregnant during the study. 4. A history of a primary seizure disorder, seizure associated with an intracranial lesion, recurrent seizures related to substance intoxication or withdrawal or recent seizure within the last 6 months. 5. Space occupying intracranial lesion. 6. Any generalized skin disorders precluding the use of the nicotine patch. 7. Any known hypersensitivity or allergies to the nicotine patch. 8. Any known life-threatening arrhythmias or severe/worsening angina pectoris. 9. Within two weeks of experiencing a myocardial infarction or cerebral vascular accident. 10. Currently using or has used nicotine replacement therapy within the past two weeks. 11. Diagnosed with a terminal illness 12. Current regular use of e-cigarettes or other vaping devices containing nicotine and not willing to stop using these devices for the duration of the study. 13. Acutely unstable medical, psychiatric, or substance use disorder comorbidity with safety concerns at the discretion of the PI or study physician. 14. Previous treatment with rTMS for smoking cessation 15. Treatment with nicotine replacement therapy anytime within the last 1 month