10-Hour eating window may stop weight regain, new study tests
NCT ID NCT07163455
First seen Jun 27, 2026 · Last updated Aug 26, 2026 · Updated 2 times
Summary
This study tests whether limiting eating to a 10-hour window each day helps overweight or obese adults maintain weight loss after losing at least 5% of their body weight. About 500 participants across China will follow either the time-restricted eating plan or standard weight-maintenance advice for 12 months. Researchers will track weight, body composition, and overall health to see if the eating window makes a difference.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Jul 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants who meet all the following conditions will be included in the trial: 1. BMI ≥ 28.0 kg/m², or BMI between 24.0-27.9 kg/m² with at least one weight-related comorbidity. 2. Age: 18-65 years. 3. Weight Loss Plan: Willing to undergo a structured weight-loss program. Exclusion Criteria: * Participants who meet any of the following conditions will be excluded from the trial: 1. Infectious Diseases: History of HIV/AIDS, active hepatitis B/C, or active tuberculosis. 2. Malignancy: History of any malignancy. 3. Organ Dysfunction:Severe hepatic impairment.Chronic kidney disease. 4. Cardiovascular/Cerebrovascular Events: History of angina, myocardial infarction, or stroke within the past 6 months. 5. Gastrointestinal Conditions:Severe gastrointestinal diseases (e.g., inflammatory bowel disease).Gastrointestinal surgery within the past 12 months. 6. Endocrine Disorders:Cushing's syndrome, hypothyroidism, acromegaly, or hypothalamic obesity. 7. Medications: Use of drugs affecting weight/energy balance (e.g., antipsychotics, weight-loss medications) within the past 6 months. 8. Pregnancy/Lactation: Currently pregnant, planning pregnancy, or breastfeeding. 9. Compliance Issues: Inability to complete the study (due to health, immigration, or other reasons). 10. Informed Consent: Unwilling or unable to provide informed consent. 11. Weight Stability: \>5% change in body weight within the past 6 months. 12. Individuals unable to use or operate a smartphone
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Army Medical Center of PLA
Chongqing, Chongqing Municipality, 400010, China
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Chengdu Seventh People's Hospital
Chengdu, Sichuan, 610213, China
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Harbin Medical University
Harbin, Heilongjiang, 150081, China
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Shenzhen People's Hospital
Shenzhen, Guangdong, 518020, China
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The Affiliated Hospital of Qingdao University
Qingdao, Shandong, 266000, China
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The Fifth Medical Center of Chinese PLA General Hospital
Beijing, Beijing Municipality, 100071, China
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The First Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, 150001, China
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The Second Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, 150086, China
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The Second Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, 710004, China
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Weifang People's Hospital
Weifang, Shandong, 261041, China
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