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Could testosterone therapy be safe for men with prostate cancer? new trial aims to find out

NCT ID NCT06733350

First seen Feb 14, 2026 · Last updated Jun 18, 2026 · Updated 21 times

Summary

This study looks at whether testosterone replacement therapy (TRT) can be safely used in men with low-risk prostate cancer that hasn't spread, and who are under active surveillance (regular check-ups instead of immediate treatment). Many men with low testosterone have symptoms like low sex drive and erectile problems, but doctors often avoid TRT because of fears it might make the cancer grow. The trial will enroll 600 men and track cancer progression, quality of life, and whether men stay on active surveillance. The goal is to see if TRT can improve well-being without increasing cancer risk.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Roswell Park Cancer Institute

    RECRUITING

    Buffalo, New York, 14263, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.