New shot may curb heavy drinking in Reward-Seeking patients
NCT ID NCT05028062
First seen Jan 25, 2026 · Last updated May 22, 2026 · Updated 12 times
Summary
This study tests whether a monthly injection of naltrexone (a medication that blocks pleasure from alcohol) helps people who drink mainly for the rewarding effects reduce their heavy drinking. About 60 adults with alcohol use disorder will receive either the shot or a placebo, plus counseling. The goal is to see if the medication leads to fewer heavy drinking days over 8 weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Pennsylvania Center for Studies of Addiction
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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