Daily injection could free kids from IV nutrition dependency

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being aged from 2 to 18 years old included ; * Presenting less than 80 cm of residual small intestine with or without the terminal ileum, ileocecal valve and right colon or having less than 120 cm in case of Short Bowel Syndrome (SBS) caused by Hirschsprung disease; * Being stable on PN support (inability to significantly reduce PN intake for the last six months before inclusion) ; * Being dependent on PN for at least 2 years and enterally fed (oral or tube feeding) ; * Having a normal colonoscopy in the 12 months before screening for children with maintained colon (=SBS type 2 or 3) older than 12 years ; * Having signed the Informed consent form (or parents or legal representative for minor patients). Exclusion Criteria: * Having a major gastrointestinal surgical intervention like serial transverse enteroplasty or any other bowel lengthening procedure performed within 6 months of screening ; * Having a clinically significant untreated intestinal obstruction or active stenosis ; * Having an unstable absorption due to cystic fibrosis or known DNA abnormalities ; * Presenting a radiographic or manometric evidence of pseudo-obstruction or severe known dysmotility syndrome, including persistent, severe gastroschisis-related motility disorders ; * Having an unstable cardiac disease, congenital heart disease or cyanotic disease, with the exception of patients who had undergone ventricular or atrial septal defect repair ; * Having a history of cancer or clinically significant lymphoproliferative disease; excepted resected cutaneous basal or squamous cell carcinoma, or in situ non-aggressive and surgically resected cancer ; * Having participated in a clinical study using an experimental drug within 1 month or an experimental antibody treatment within 3 months prior to screening, or concurrent participation in any clinical study using an experimental drug that would affect the safety of teduglutide ; * Having already used native GLP-2 and glucagon-like peptide-1 analog or human growth hormone within 3 months prior to screening ; * Having already used oral or IV glutamine, octreotide, or dipeptidyl peptidase IV (DPP-IV) inhibitors within 3 months prior to screening ; * Having an active Crohn's disease which has been treated with biological therapy within the 6 months prior to screening ; * Having an intestinal polyposis; * Being, for female patient, both lactating and breast-feeding or having a positive pregnancy test during the screening period; * Refusing the follow the protocol requirements in terms of birth control ; * Being unable to follow the study procedures for any reason: psychological, geographical… * Hypersensitivity to the active substance or to any of the excipients listed in section 6.1 of Summary of Product Characteristics (SPC), or trace residues of tetracycline. * Active or suspected malignancy. * Patients with a history of malignancies in the gastrointestinal tract including the hepatobiliary system within the last five years.