Warm eyelid therapy offers hope for young dry eye sufferers
NCT ID NCT07579156
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a device called TearCare that warms the eyelids and manually clears blocked oil glands in young adults (ages 18-29) with dry eye disease. 45 participants will receive one treatment and be checked after 4 weeks to see if symptoms and tear film stability improve. The goal is to ease discomfort and improve quality of life.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 45 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 29 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age ≥18 years but \<30 years of age 2. Non-invasive Keratograph break-up time (NIKBUT) \<10 seconds in at least one eye 3. Meibomian gland secretion score (MGSS) ≤23 for 15 glands in at least one eyelid 4. OSDI ≥23 Exclusion Criteria: 1. Contact lens wear within two weeks of study enrollment or planned during study period 2. Habitual visual acuity worse than 0.30 logMAR (Snellen equivalent of 20/40) in either eye 3. Previous or current diagnosis of any autoimmune condition 4. Use of any of the following medications within 60 days of enrollment: 1. Topical ophthalmic cyclosporine (including but not limited to Restasis®, Cequa®, Vevye®, generic, or compounded versions) 2. Xiidra® 3. Miebo® 4. Tyrvaya® 5. Tryptyr® 5. Use of topical ocular steroids within 30 days of enrollment 6. Use of any other topical ophthalmic drop, excluding artificial tears, within 7 days 7. Use of oral tetracyclines or oral azithromycin within 30 days 8. Present or past use of oral isotretinoin 9. Any of the following procedural treatments for MGD in the past: 1. LipiFlow® 2. TearCare® 3. iLux® 4. Intense pulsed light (IPL) 10. Previous intraocular surgery within 6 months of enrollment 11. Previous refractive surgery within 2 years of enrollment 12. Current or planned pregnancy during the study period 13. Current or planned lactation during the study period 14. Females of childbearing potential who are not using effective contraception 15. Dose modification of oral antihistamines or antidepressants within 30 days of enrollment 16. Current enrollment or enrollment within 60 days in any other study of an investigational drug or device 17. Clinical opinion of the study doctor based on clinical examination and/or participant compliance with protocol requirements
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Alabama at Birmingham, School of Optometry, Clinical Eye Research Facility
Birmingham, Alabama, 35294, United States
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Other studies related to the condition(s) this trial covers.
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