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Light Therapy's secret: scientists probe tear changes for dry eye clues

NCT ID NCT07329712

Knowledge-focused Sponsor: Singapore National Eye Centre Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how low-level light therapy changes tear proteins in people with dry eye disease. Researchers want to understand how the therapy works and find markers that show who will respond well. About 30 adults will have their tears tested before and after treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patient undergoing low level light therapy that met the study inclusion and exclusion

Ages

21 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Must be eligible for, and have consented for low level light therapy 2. Must not have presented to the clinic for an acute eye problem such as visual loss or painful eye 3. Ability to give informed consent. 4. Age more or equals to 21 years old. Exclusion Criteria: 1. Patients who are unable to or decline to give consent. 2. Age less than 21 years old. 3. Patients who presented to the clinic for an acute eye problem such as visual loss or painful eye. 4. Patients not suitable for low level lighttherapy: * Pregnant * Fitted with pacemakers, metal, electrical, acoustic prosthetics * Epilepsy, cardiac rhythm or frequency disorders * Fever, thrombophlebitis or acute phlebitis of the legs, large-sized varicose veins, or venous surgery within 2 months * Uncontrolled hypertension or severe diabetes * Open wounds on eyelid or skin * Evolving cancer or hepatitis * Blood anticoagulant or coagulation defect

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Conditions

The condition(s) this trial relates to.

dry eye syndrome Meibomian Gland Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dry eye Meibomian gland dysfunction (disorder)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Singapore Eye Research Insititute

    RECRUITING

    Singapore, Singapore

More trials for these conditions

Other studies related to the condition(s) this trial covers.