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Tai chi for brain health: study aims to personalize exercise for memory loss

NCT ID NCT07608510

Knowledge-focused Sponsor: Lidian Chen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at 150 older adults with mild cognitive impairment who already practice Tai Chi regularly. Researchers want to see if a computer model can predict who gets the most cognitive benefit and what dose works best. It's an observational study, meaning no one is assigned to Tai Chi—it just observes existing habits to validate a prediction tool.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
24-form Simplified Tai Chi (observational, not assigned)
What this could lead to
If successful, this could help doctors personalize Tai Chi recommendations for elderly with mild cognitive impairment, improving cognitive benefits.
What could go wrong
This is an observational study, not a trial of a new treatment. It only validates an existing model, so it won't prove Tai Chi works—just who might benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This cross-sectional real-world external validation study will enroll 150 community-dwelling older adults aged 60 years and above, who are diagnosed with Mild Cognitive Impairment (MCI) and have regular practice of standardized 24-form simplified Tai Chi for at least 6 months (consistent with the form used in the parent RCTs). Eligible participants will be recruited from communities in Fuzhou, China, to validate the generalizability and clinical applicability of a pre-developed machine learning prediction model for Tai Chi cognitive benefit population identification.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1\. Presence of mild cognitive impairment, not demented; 2. Age ≥ 60 years old; 3.Regular practice of standardized 24-form simplified Tai Chi for at least 6 months (consistent with the form used in the parent randomized controlled trials \[RCTs\]) ; 4.Informed consent and voluntary participation. Exclusion Criteria: 1. Geriatric Depression Scale score ≥ 9 points 2. Cognitive impairment caused by other reasons, taking drugs, poisoning, etc; 3. Suffer from severe musculoskeletal system diseases and other contraindications to exercise and are not suitable for Tai Chi training, such as those who suffer from stroke, Parkinson's disease, and have a history of lower limb arthritis, hip and knee joint replacement, etc; 4. Patients with severe heart, liver, kidney failure, malignant tumors, and other major diseases; 5. Individuals with visual/auditory impairments, writing/reading impairments, illiteracy, etc. that affect training and evaluation; 6. Individuals with uncontrolled hypertension (systolic blood pressure greater than 160mmHg or diastolic blood pressure greater than 100mmHg after medication); 7. Participating in other experiments that influence this study. -

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mild cognitive impairment (MCI)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

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Other studies related to the condition(s) this trial covers.