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Can a gut health supplement and more fruits help fight obesity?

NCT ID NCT05459909

Disease control Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether taking a synbiotic supplement (a mix of probiotics and prebiotics) and eating more fruits and vegetables can lower the risk of obesity and related health problems in Hong Kong Chinese adults. One hundred overweight or obese participants will follow the diet and/or take the supplement for eight weeks. Researchers will measure changes in body weight, body fat, and markers of metabolic health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
synbiotic supplement (probiotics plus prebiotics) and increased fruits and vegetables
What this could lead to
If it works, this could point toward a simple dietary strategy to lower obesity risk and improve metabolic health.
What could go wrong
This is a small, early-stage study with only 100 participants over 8 weeks. Results may not apply to other populations or lead to lasting weight loss.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2020

Expected to finish

Jul 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 95 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Waist circumference ≥90cm in men and ≥80cm in women * BMI \>23.0kg/m2 Exclusion Criteria: * Practicing dietary restrictions * Using cholesterol-lowering, antihypertensive, anti-inflammatory drugs or Chinese medicines * Consuming laxatives, any gastrointestinal medication, probiotics, prebiotics, synbiotics or antibiotics * Smokers * Alcohol abuser * Currently pregnant or lactating

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity

Contacts and locations

Locations

  • The Chinese University of Hong Kong

    Shatin, 000000, Hong Kong

More trials for these conditions

Other studies related to the condition(s) this trial covers.