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Clip vs stitch: which secures the appendix better in keyhole surgery?

NCT ID NCT07689123

Disease control Sponsor: Universiti Sains Malaysia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial compares two ways to seal the base of the appendix during keyhole surgery: a single surgical clip versus traditional suture ligatures. The goal is to see which method leads to fewer complications, shorter hospital stays, and lower costs. Adults scheduled for laparoscopic appendicectomy are randomly assigned to one of the two techniques and followed up one month after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
surgical clip (XXL Click'aV Plus, Grena) or suture ligature
What this could lead to
If one method proves safer or faster, it could become the preferred technique for appendix removal, reducing complications and hospital stays.
What could go wrong
This is a small, single-center trial with only 64 participants, so results may not apply broadly. Both methods are already in use, so major breakthroughs are unlikely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

64 people

The number who actually took part.

Started

Jul 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age \>18 years old 2. Both genders 3. Planned for laparoscopic appendicectomy Exclusion Criteria: 1. Patient not consented 2. Appendix perforated at base or unhealthy appendix base 3. Conversion to open appendicectomy 4. Diagnosed with other pathology intra-operatively 5. Pregnant patients

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Conditions

The condition(s) this trial relates to.

appendicitis disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Appendicitis (diagnosis)

Contacts and locations

Locations

  • Hospital Seberang Jaya

    Seberang Jaya, Pulau Pinang, 13700, Malaysia

More trials for these conditions

Other studies related to the condition(s) this trial covers.