New nerve block could cut morphine use after hip surgery

NCT ID NCT06982625

Symptom relief Sponsor: Institut Mutualiste Montsouris Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a nerve block called Supra-Inguinal Fascia Iliaca Block (SIFIB) can help patients who have severe pain after hip replacement surgery. The block is given only to those in significant pain, aiming to reduce morphine use and help them walk sooner. Researchers will enroll 310 patients and measure pain relief, morphine needs, and ability to walk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: local anesthetic (ropivacaine)
What this could lead to: If it works, this could give doctors a reliable rescue option for severe pain after hip replacement, reducing morphine use and speeding up recovery.
What could go wrong: This is a small, early-stage study testing a technique that hasn't been proven effective for all hip replacement patients. The nerve block may cause temporary muscle weakness, which could delay walking.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 310 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patient scheduled for a primary total hip arthroplasty under general anesthesia, * written informed consent. Non inclusion criteria: * contra indication to ropivacaine * vulnerable person Exclusion Criteria: * per-operative complication making wheight-bearing and walking contra-indicated. * patient without significant pain post-operatively.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hip arthroplasty, total Nerve block Post operative pain, acute

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

New nerve block could cut morphine use after hip surgery

What the study statuses mean