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Neck surgery pain relief: could a simple injection replace opioids?

NCT ID NCT06755736

Symptom relief Sponsor: Medipol University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Aug 18, 2026 · Updated 9 times

Summary

This study tested whether a superficial cervical block—a local anesthetic injection in the neck—can reduce the need for opioid painkillers after anterior cervical discectomy surgery. Sixty adults scheduled for this neck surgery were randomly assigned to receive either the block or standard care. Researchers measured how much rescue opioid (tramadol) patients needed and compared pain scores. The goal is to find a safer, effective pain control method that avoids opioid side effects like nausea and breathing problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
superficial cervical plexus block (local anesthetic injection)
What this could lead to
If it works, this could offer a safer way to manage pain after neck surgery, reducing reliance on opioids and their side effects.
What could go wrong
This is a small, completed trial with only 60 patients. The block may not significantly reduce opioid use or pain scores, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

48 people

The number who actually took part.

Started

Jan 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged between 18 and 70 years * American Society of Anesthesiologists (ASA) physical status I-II * Scheduled for unilateral single- or two-level microscopic anterior cervical discectomy and fusion (ACDF) under general anaesthesia Exclusion Criteria: * History of bleeding diathesis, * Receiving anticoagulant treatment, * Known local anesthetics and opioid allergy, * History of chronic pain * Infection of the skin at the site of the needle puncture, * Patients who do not accept the procedure

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain Superficial cervical block

Contacts and locations

Locations

  • Medipol University

    Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.