Brain scans may predict arm recovery after stroke
NCT ID NCT05332652
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to understand how the brain changes after a stroke and how those changes relate to arm recovery. Researchers will use brain scans and electrical recordings to build a model that predicts recovery. The goal is to eventually personalize brain stimulation therapy to improve rehabilitation. The study involves 41 recent stroke patients and healthy volunteers.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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41 people
The number who actually took part.
- Started
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Sep 2020
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
* Inclusion criteria for stroke patients: 1. 21-80 years old; 2. First ever stroke less than 6 weeks; 3. Moderate to severe upper limb impairment with Manual Muscle Testing (MMT) score on shoulder abduction plus finger extension (SAFE) \<5 within the first week post-stroke. * Inclusion criteria for healthy subjects: 1. Age 21-80 years old; 2. No known medical history. * Exclusion criteria for stroke patients: 1. Pregnancy; 2. Any metal implants inside the body that are contraindications of MRI scan; 3. cardiac pacemakers; 4. History of epilepsy; 5. Sensorimotor disturbance due to other causes other than stroke; 6. Claustrophobia; 7. Uncontrolled medical conditions including hypertension, diabetes mellitus and unstable angina; 8. Major depression and a history of psychotic disorders; 9. Terminal diagnosis with life expectancy \<=1 year. * Exclusion criteria for healthy subjects: 1. Pregnancy; 2. Any metal implants inside the body that are contraindications of MRI scan; 3. cardiac pacemakers; 4. Claustrophobia.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Alexandra Hospital
Singapore, Singapore
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National University Hospital
Singapore, Singapore
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Other studies related to the condition(s) this trial covers.
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