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Can a robot unlock the Brain's recovery after stroke?

NCT ID NCT04171856

Knowledge-focused Sponsor: University Hospital of Mont-Godinne Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study investigates whether people who recently had a stroke (within 21 days) can learn new arm movements using a rehabilitation robot called REAplan. Researchers will compare their learning ability with healthy individuals and those who had a stroke long ago. The goal is to understand how different brain regions affected by stroke influence motor skill learning, which could inform future rehabilitation approaches.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
REAplan(R) rehabilitation robot for motor skill learning with the affected arm
What this could lead to
If successful, this could reveal how the brain learns motor skills after stroke, potentially guiding more effective rehabilitation strategies.
What could go wrong
This is an exploratory study, not a treatment trial. Results may not translate into direct clinical benefits, and individual outcomes could vary widely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 245 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2020

Expected to finish

Jul 2040

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

ACUTE STROKE PATIENTS: Inclusion Criteria: * acute stroke (\> 21 days) * aged 18-90 years * with a stroke lesion on brain imaging Exclusion Criteria: * " classical " contre-indication to MRI (non-MR-compatible pacemaker, pregnancy, non-MR-compatible implanted devices, claustrophoby, etc ...) * difficulty in understanding or executing commands * drug/alcohol abuse * severe aphasia / cognitive deficits interfering with study * inability to voluntarily move the affected arm (i.e. complete paralysis of the arm) * multiple strokes / dementia / psychiatric condition PATIENTS WITH TRANSIENT GLOBAL AMNESIA: Clinical diagnosis, criteria of Hodge \& Warlow (1990): * Anterograde amnesia observed by a witness * No alteration of consciousness or loss of identity * Cognitive dysfunction limited to amnesia * Lack of focused neurological deficit or argument for a comitiality * Absence of head trauma * Symptom resolution within 24 hours * Possible existence of vegetative symptoms Inclusion criteria: * Transient global amnesia * 8-90 years old * Be able to perform 3 consecutive sessions on a rehabilitation robot Exclusion criteria: * Severe aphasia / cognitive deficits interfering with study * Psychiatric disorders * Alcohol / drug addiction * Exclusion criteria related to MRI HEALTHY INDIVIDUALS: Inclusion Criteria: • 18-90 years Exclusion Criteria: * medical history with a previous stroke/neurological deficit * drug/alcohol abuse * psychiatric condition/ dementia CHRONIC STROKE PATIENTS: Inclusion Criteria: * chronic stroke (\>6 months) * aged 18-90 years * with a stroke lesion on brain imaging Exclusion Criteria: * difficulty in understanding or executing commands * drug/alcohol abuse * severe aphasia / cognitive deficits interfering with study * inability to voluntarily move the affected arm (i.e. complete paralysis of the arm) * multiple strokes / dementia / psychiatric condition

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Conditions

The condition(s) this trial relates to.

stroke disorder transient global amnesia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke, acute

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHU UCL Namur

    RECRUITING

    Yvoir, Namur, 5530, Belgium

  • University Hospital CHU Dinant Godinne UCL

    NOT_YET_RECRUITING

    Yvoir, 5530, Belgium

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