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New hope for CGD: stem cell transplant breakthrough trial

NCT ID NCT05463133

First seen Mar 27, 2026 · Last updated May 21, 2026 · Updated 7 times

Summary

This study tests whether adding special drugs (IL-6 and IFN-gamma blockers) to the standard stem cell transplant process can help cure chronic granulomatous disease (CGD), a condition that makes people prone to severe infections. About 50 people aged 4 to 65 with CGD will receive donor stem cells after a tailored treatment plan. The goal is to improve survival and reduce infections after transplant.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.