Could a neck injection stop Post-Surgery heart flutters?
NCT ID NCT06271707
First seen Jun 26, 2026 · Last updated Aug 11, 2026 · Updated 2 times
Summary
This pilot study tests whether a left-sided stellate ganglion block using bupivacaine can lower the rate of atrial fibrillation after esophagectomy, pneumonectomy, or lobectomy. 48 adults aged 18-85 undergoing these surgeries will receive either the nerve block or a saline placebo. The main goal is to see if the block reduces atrial fibrillation in the first week after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine
- What this could lead to
- If it works, this could point toward a simple injection to prevent a common heart rhythm problem after major chest surgery.
- What could go wrong
- This is a very small pilot study with only 48 people, so results may not be conclusive. The nerve block itself carries rare risks like bleeding or nerve damage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 48 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients undergoing esophagectomy, pneumonectomy, or lobectomy aged 18-85. Exclusion Criteria: * Patients who have an exclusion to regional anesthesia. * Patients who have exclusion to stellate blockade. * Patients who are pregnant assessed via self-report or pregnancy test if they have taken one
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
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