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Could a common cholesterol drug improve recovery after cancer surgery?

NCT ID NCT01169051

Knowledge-focused Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study reviewed the medical records of 569 adults who had surgery for lung or esophageal cancer. Researchers wanted to see if taking statins (cholesterol-lowering drugs) around the time of surgery was linked to fewer complications and better long-term outcomes. The goal is to find out if a simple, inexpensive drug could help patients recover more smoothly.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
statins
What this could lead to
If statins are found to improve recovery, this could point toward a simple way to reduce complications after thoracic cancer surgery.
What could go wrong
This is a retrospective review, not a controlled trial, so it can only show an association, not prove cause and effect. Results may not lead to changes in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

569 people

The number who actually took part.

Start date

Jul 2010

Finished

May 2012

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study is a retrospective chart review of adult thoracic surgery patients who underwent: * Esophagectomy * Pulmonary wedge resection * Pulmonary lobectomy * Pulmonary pneumonectomy Data collected will be from January 1, 2007 forward.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: This study is a retrospective chart review of adult thoracic surgery patients who underwent: * Esophagectomy * Pulmonary wedge resection * Pulmonary lobectomy * Pulmonary pneumonectomy Data collected will be from January 1, 2007 forward Exclusion Criteria: None

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Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms lung cancer lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Esophagectomy Pulmonary lobectomy Pulmonary pneumonectomy Pulmonary wedge resection

More trials for these conditions

Other studies related to the condition(s) this trial covers.