New contact lens takes on popular brand in vision showdown
NCT ID NCT07345416
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new daily disposable contact lens called ST-1 against an existing lens, Miru 1day UpSide, in 63 people with nearsightedness. Participants will wear the lenses daily for 3 months and have their vision and eye comfort checked regularly. The goal is to see if the new lens works as well or better for correcting vision and keeping eyes comfortable.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ST-1 silicone hydrogel daily disposable soft contact lenses
- What this could lead to
- If successful, this could show that ST-1 lenses are a safe and effective option for daily myopia correction, offering similar or better comfort and vision than existing lenses.
- What could go wrong
- This is a small, early-stage study with only 63 participants, so results may not apply to everyone. There is always a risk of discomfort or eye health issues with contact lenses.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 63 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
May 2026
An estimate. Start dates often move.
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 40 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. With either gender aged between 18 to 40 (inclusive) years old. 2. Diagnosis of myopia in both eyes, each ranging from -0.50D to 6.00D with manifest astigmatism of ≤ 1.00D per eye. 3. Understands and signs an informed consent form (ICF). 4. Willing to adhere to the instructions set forth in this study as well as understand and complete all specified evaluation. 5. Willing and able to refrain from using any other contact lenses other than those provided for the duration of the study. 6. Has experience and capability of wearing soft contact lenses. 7. Be a habitual soft contact lenses wearer in both eyes, defined as wearing lenses for at least 8 hours per day, 5 days per week, for a minimum duration of 30 days. 8. Tear breakup time (TBUT) \> 5 seconds in each eye. Exclusion Criteria: 1. Eyes with abnormality or disease as follows: 1. Evidence of lid abnormality or infection (e.g., entropion, ectropion, chalazia, and recurrent styes). 2. Clinically significant slit lamp findings (e.g., infiltrates or other slit lamp findings Level 2 or above: corneal edema, tarsal abnormalities, and conjunctival injection). 3. Other active ocular disease (e.g., uveitis, corneal epithelial defect, severe dry eye, lacrimal duct defect, glaucoma, cornea \[infiltrates\], conjunctiva, lids, and intraocular infection or inflammation of an allergic, bacterial, or viral etiology). 4. History of recurrent corneal erosions. 5. Aphakia. 2. Ocular or systemic allergies or diseases that may interfere with contact lens wear, occur within 2 weeks prior to the Screening Visit. 3. Use of topical ocular medications, except artificial tear, within 7 days prior to the Screening Visit. 4. History of refractive, ocular, or intraocular surgery. 5. Participation in any clinical trial (with the exception of retrospectives studies) within 30 days prior to the Screening Visit. 6. Have risks in dangerous and significant eye edema, congestions, corneal abrasion or neovascularization when wearing contact lens. 7. Any corneal surface roughness. 8. Unable to achieve best corrected visual acuity (BCVA) of logMAR 0.1 or better in each eye at distance using manifest refraction. 9. Females who are pregnant, breastfeeding or who intend to become pregnant over the course of the study. 10. Current drug or alcohol use or dependence that, in the opinion of the Investigator, would interfere with adherence to study requirement. 11. Allergy to any component in the study product. 12. Subjects who wore monovision, multifocal, toric, or rigid contact lenses within 30 days prior to the Screening Visit. Note: Monovision is defined as a vision correction method for treating presbyopia in which the dominant eye is corrected for distance vision and the non-dominant eye is corrected for near vision. 13. Use of systemic medications (e.g., chronic steroid use) that are known to interfere with contact lenses wear at the Investigators discretion within 14 days prior to the Screening Visit. 14. Other conditions not suitable for participating in this study judged by the Investigators. 15. Live in dusty or pharmaceutical environments.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Daily disposable soft contact lenses are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
6 sites. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Chang-Gung Memorial Hospital LinKou Branch
Taoyuan, Taoyuan City, 33305, Taiwan
-
Changhua Christian Hospital
Changhua, Changhua City, 50006, Taiwan
-
Far Eastern Memorial Hospital
New Taipei City, New Taipei City, 220, Taiwan
-
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, Kaohsiung City, 80756, Taiwan
-
Taipei Veterans General Hospital
Taipei, Taipei City, 11217, Taiwan
-
Tri-Service General Hospital
Taipei, Taipei City, 114202, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Two lens designs go Head-to-Head for aging eyes
- Can AI protect Kids' eyesight where eye doctors are scarce?
- Two toric lenses go head to head in vision test
- Eye scans as a window to the body: study probes retinal imaging across diseases
- Lens showdown: which contact lens wins in dim light?
- Myopia glasses may keep working even after kids take them off