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Two lens designs go Head-to-Head for aging eyes

NCT ID NCT07829419

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers compare two monthly replacement silicone hydrogel multifocal toric contact lenses in people over 40 who already wear soft contacts. The study measures how easy the lenses are to handle, especially removal, and other performance factors. About 60 participants with astigmatism and presbyopia take part, trying both lens designs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Two monthly replacement silicone hydrogel multifocal toric contact lenses (comfilcon A and lehfilcon A)
What this could lead to
If one lens design performs better, it could help eye care professionals recommend a more comfortable and easier-to-handle option for people who need both astigmatism correction and reading help.
What could go wrong
This is a small, short comparison study. Results may not apply to everyone, and lens comfort and handling can vary widely from person to person. Neither lens may clearly outperform the other.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: A person is eligible for inclusion in the study if they are: 1. Participants at least 40 years of age. 2. Participants requiring lens powers within the range available for the study lenses. 3. Participants with a spherical refractive error at the corneal plane of plano to -6.00. 4. Participants with a minimum reading add of +0.75DS (based on their spectacle refraction at screening). At least 12 participants will be enrolled per add group: low (+0.75 to +1.25D), medium (+1.50 to +1.75D), and high (+2.00 to +2.50). 5. Participants with refractive astigmatism at the corneal plane of 0.75 to 2.00DC. 6. Best spectacle corrected visual acuity greater than or equal to 20/25 (less than or equal to LogMAR 0.1). 7. Habitually using soft contact lenses (multifocal soft contact lenses, sphere or toric lenses for monovision, or sphere or toric lenses for distance vision correction and spectacles for near vision correction) and have worn lenses at least 3 days a week for at least the past six months. 8. Anticipating being able to wear contact lenses for at least 8 hours a day, 5 days a week. 9. Willing and able to follow instructions and maintain the appointment schedule. Exclusion Criteria: 1. Anterior segment infection, inflammation or abnormality that would contraindicate contact lens wear. 2. Any active anterior segment ocular disease that would contraindicate contact lens wear. 3. The use of systemic or ocular medications that would contraindicate contact lens wear. 4. History of herpetic keratitis. 5. History of refractive surgery or irregular cornea. 6. Slit lamp findings that are more serious than grade 1 (see ISO 11980 scale). 7. Inactive (i.e. ghost) vessels greater than 1 mm of penetration into the cornea. 8. Participation of the participant in a contact lens or contact lens care product clinical trial within the previous 90 days if involving orthokeratology, 30 days if involving extended wear, rigid gas permeable corneal and scleral lenses, or 15 days if involving daily disposable, daily wear soft lenses.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    3 sites. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Drs. Mcintyre Garza Avila & Jurica

    Corpus Christi, Texas, 78411, United States

  • ProCare Vision Center

    Granville, Ohio, 43023, United States

  • Sacco Eye Group

    New York, New York, 13850, United States

    Contact Email: •••••@•••••

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