Two lens designs go Head-to-Head for aging eyes
NCT ID NCT07829419
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
Researchers compare two monthly replacement silicone hydrogel multifocal toric contact lenses in people over 40 who already wear soft contacts. The study measures how easy the lenses are to handle, especially removal, and other performance factors. About 60 participants with astigmatism and presbyopia take part, trying both lens designs.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Two monthly replacement silicone hydrogel multifocal toric contact lenses (comfilcon A and lehfilcon A)
- What this could lead to
- If one lens design performs better, it could help eye care professionals recommend a more comfortable and easier-to-handle option for people who need both astigmatism correction and reading help.
- What could go wrong
- This is a small, short comparison study. Results may not apply to everyone, and lens comfort and handling can vary widely from person to person. Neither lens may clearly outperform the other.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Sep 2026
An estimate. Start dates often move.
- Expected to finish
-
Sep 2027
An estimate. End dates often move.
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
40 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: A person is eligible for inclusion in the study if they are: 1. Participants at least 40 years of age. 2. Participants requiring lens powers within the range available for the study lenses. 3. Participants with a spherical refractive error at the corneal plane of plano to -6.00. 4. Participants with a minimum reading add of +0.75DS (based on their spectacle refraction at screening). At least 12 participants will be enrolled per add group: low (+0.75 to +1.25D), medium (+1.50 to +1.75D), and high (+2.00 to +2.50). 5. Participants with refractive astigmatism at the corneal plane of 0.75 to 2.00DC. 6. Best spectacle corrected visual acuity greater than or equal to 20/25 (less than or equal to LogMAR 0.1). 7. Habitually using soft contact lenses (multifocal soft contact lenses, sphere or toric lenses for monovision, or sphere or toric lenses for distance vision correction and spectacles for near vision correction) and have worn lenses at least 3 days a week for at least the past six months. 8. Anticipating being able to wear contact lenses for at least 8 hours a day, 5 days a week. 9. Willing and able to follow instructions and maintain the appointment schedule. Exclusion Criteria: 1. Anterior segment infection, inflammation or abnormality that would contraindicate contact lens wear. 2. Any active anterior segment ocular disease that would contraindicate contact lens wear. 3. The use of systemic or ocular medications that would contraindicate contact lens wear. 4. History of herpetic keratitis. 5. History of refractive surgery or irregular cornea. 6. Slit lamp findings that are more serious than grade 1 (see ISO 11980 scale). 7. Inactive (i.e. ghost) vessels greater than 1 mm of penetration into the cornea. 8. Participation of the participant in a contact lens or contact lens care product clinical trial within the previous 90 days if involving orthokeratology, 30 days if involving extended wear, rigid gas permeable corneal and scleral lenses, or 15 days if involving daily disposable, daily wear soft lenses.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Astigmatism are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The study's own enquiry address
This study publishes an address for enquiries. See it below .
-
The places running it
3 sites. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
-
Drs. Mcintyre Garza Avila & Jurica
Corpus Christi, Texas, 78411, United States
-
ProCare Vision Center
Granville, Ohio, 43023, United States
-
Sacco Eye Group
New York, New York, 13850, United States
Contact Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A lens that could let cataract patients see near and far without glasses
- Can AI protect Kids' eyesight where eye doctors are scarce?
- Two toric lenses go head to head in vision test
- Eye scans as a window to the body: study probes retinal imaging across diseases
- Lens showdown: which contact lens wins in dim light?
- Myopia glasses may keep working even after kids take them off