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Splint or exercise? new study aims to settle best treatment for thumb tendonitis

NCT ID NCT06995534

Symptom relief Sponsor: Konya Beyhekim Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two common conservative treatments for De Quervain's tenosynovitis, a painful thumb tendon condition: a static hand-wrist splint versus home-based exercise therapy. Forty adults with acute or subacute pain will be tracked for changes in pain, wrist function, and tendon swelling. The goal is to find which approach works better so doctors can offer clearer, evidence-based guidance.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
static hand-wrist splint and home-based exercise therapy
What this could lead to
If this trial succeeds, it could point toward a clearer, evidence-based first-choice treatment for De Quervain's tenosynovitis, reducing pain and improving hand function without surgery.
What could go wrong
This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. There is also no guarantee that either treatment will prove clearly better than the other.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged between 18 and 65 years Patients experiencing wrist pain and tenderness for less than 3 months and clinically diagnosed with acute or subacute De Quervain's tenosynovitis Visual Analog Scale (VAS) pain score ≥ 3 Exclusion Criteria: * History of trauma Wrist fractures Local infection Presence of rheumatologic diseases (e.g., rheumatoid arthritis, psoriatic arthritis) Presence of symptomatic hand osteoarthritis Continuous use of nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids Receipt of physical therapy for the hand or wrist within the past 3 months Corticosteroid injection into the hand or wrist within the past 3 months Diagnosed with significant neurological disorders (e.g., upper motor neuron disease) Presence of uncontrolled systemic diseases (e.g., uncontrolled diabetes mellitus, congestive heart failure, chronic kidney disease, hepatic failure) Major psychiatric disorders Communication difficulties

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Conditions

The condition(s) this trial relates to.

agnosia de Quervain disease nephrotic syndrome 14 Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

De quervains tenosynovitis Exercise therapy Pain management Splints Ultrasonographic

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Konya Beyhekim Training and Research Hospital

    RECRUITING

    Konya, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.