Could a $10 pill help flush out hidden HIV? small study aims to find out.
NCT ID NCT07415811
First seen Feb 21, 2026 · Last updated May 19, 2026 · Updated 12 times
Summary
This early-stage study tests whether spironolactone, a drug already approved for high blood pressure, can reduce the hidden HIV reservoir in people on effective antiretroviral therapy. Twelve adults (both HIV-negative and HIV-positive) will take the drug for a short time, and researchers will measure changes in a protein called XPB that HIV needs to survive. The goal is to gather initial safety and biological data to see if this approach could one day lead to a cure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Grupo de Pesquisa Clínica em Moléstias Infecciosas
São Paulo, São Paulo, 05401000, Brazil
Conditions
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