University Of Sao Paulo General Hospital

This study is testing a live attenuated dengue vaccine (Butantan-DV) in 477 people aged 12–59 with stable autoimmune rheumatic diseases (like rheumatoid arthritis or lupus) and in healthy volunteers. The goal is to see if the vaccine is safe and produces a strong immune response …

This study is testing a non-invasive chest monitor called electrical impedance tomography (EIT) to see if it can accurately detect pulmonary hypertension, a serious lung condition. Currently, diagnosis requires an invasive procedure called right heart catheterization. If successf…

This study compares video lessons to traditional reading for treating binge eating disorder. Eighty adults will receive either weekly videos or text-based readings, plus six short online sessions with a psychologist. The goal is to see if video-based therapy can reduce binge eati…

This study tests whether treating jaw joint disorder with a stabilizing mouth splint can reduce ringing in the ears (tinnitus) that is linked to jaw issues. About 63 adults with both tinnitus and jaw problems for over 6 months will receive either a real splint or a placebo. Resea…

This study tests two treatments for vaginal dryness in women with Sjögren's disease: a special laser and a topical hormone cream. About 60 women will be randomly assigned to one of the two treatments. The goal is to see which approach better improves vaginal health and sexual fun…

This study looks at whether tiny particles released by cells into the blood, called extracellular vesicles, can help detect heart damage from ATTR amyloidosis earlier and less invasively. Researchers will compare these particles in 70 people with different forms of ATTR amyloidos…

This study is creating and testing a questionnaire to see how much people with pulmonary arterial hypertension (PAH) know about their condition. Researchers will check if the questions make sense to patients and experts. Up to 200 adults with PAH will take part. The goal is to ha…

This study compares two video laryngoscopes—the McGRATH™ MAC and the BESDATA BD-DF—for placing breathing tubes in infants during surgery. About 226 children aged 6 months to 3 years will be randomly assigned to one device. The goal is to see if the BESDATA works as well as the Mc…