University Of Sao Paulo General Hospital

This study looks at whether temporarily stopping methotrexate (an arthritis medication) for 2 weeks after a pneumonia vaccine (PCV20) helps the vaccine work better in adults with autoimmune rheumatic diseases like rheumatoid arthritis or lupus. About 192 participants with stable,…

This study tests whether taking acyclovir daily can prevent herpes simplex outbreaks in people with autoimmune rheumatic diseases (like lupus or rheumatoid arthritis) who often get herpes. About 62 participants will receive either acyclovir or a placebo for 12 months, then be mon…

This study will test a smartphone app called CONEMO in 12,400 adults visiting primary care clinics for depression, anxiety, or insomnia. The app has already shown it can help with depression. Researchers want to see if it also improves anxiety and sleep problems. Participants wil…

This study uses a short questionnaire to find out where patients with pulmonary hypertension and their caregivers look for health information, what topics they search for, and how satisfied they are with what they find. The goal is to improve communication and educational materia…