New ultrasound technique reveals how spine stiffens after fusionless surgery
NCT ID NCT04969770
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study used ultrasound to measure how the spine stiffens over time in children with neuromuscular scoliosis who had a new type of fusionless surgery. The researchers followed 36 participants, including those who had the surgery, those with the condition but no surgery, and healthy controls, for up to 2 years. The goal was to understand the biomechanical changes in the spine after this innovative procedure.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors understand how the spine stiffens after this new surgery, potentially improving future treatments for neuromuscular scoliosis.
- What could go wrong
- This was a small, observational study with only 36 participants. It measured stiffness but did not test a treatment, so it cannot directly lead to a cure or new therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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36 people
The number who actually took part.
- Started
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Jan 2022
- Finished
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Jul 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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10 to 17 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Minor patients between 10 and \<18 years old, presenting a neuromuscular pathology, with progressive scoliosis, to undergo for their clinical care a fusionless surgery based on a bipolar spine construct, performed by a minimally invasive approach * Minor patients between 10 and \<18 years old, presenting a neuromuscular pathology such as encephalopathy / infantile spinal amyotrophy / myopathy, without progressive scoliosis * Minor patients between 10 and \<18 years old, healthy controls, followed in orthopedics for a pathology other than neuromuscular or spinal deformity * Written informed consent Exclusion Criteria: * No social insurance * Severe mental retardation or severe dystonia making data acquisition impossible or requiring sedation * Patients with gastrostomy or tracheostomy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital Necker-Enfants Malades
Paris, 75015, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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