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New study seeks to predict who walks again after cancer paralysis

NCT ID NCT07527728

Knowledge-focused Sponsor: Shanghai Changzheng Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 150 adults with paralysis from spinal tumors who undergo surgery to relieve pressure on the spinal cord. Researchers track how well patients recover movement, bladder and bowel function, and quality of life over one year. The goal is to identify factors that help predict recovery, so doctors can better advise patients and plan treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population includes adult patients (aged 18-80 years) diagnosed with spinal metastases resulting in motor paralysis, who are scheduled to undergo surgical decompression and/or stabilization. All participants must be physically fit for surgery, provide written informed consent, and be able to complete postoperative neurological assessments. Patients with cognitive impairment, pregnancy, or incomplete follow-up data will be excluded.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age between 18 and 80 years at the time of enrollment. 2. Clinical diagnosis of spinal metastases with resulting motor paralysis. 3. Scheduled for surgical decompression and/or spinal stabilization. 4. Medically fit to undergo surgery as determined by preoperative evaluation. 5. Ability to understand the study and provide written informed consent. 6. Willingness and ability to complete neurological and functional follow-up assessments. Exclusion Criteria: 1. Medically unfit for surgery due to unstable comorbidities or poor general condition. 2. Pregnant or breastfeeding at the time of enrollment. 3. Significant cognitive impairment or psychiatric illness that interferes with informed consent or study participation. 4. Expected difficulty in completing follow-up assessments or anticipated loss to follow-up. 5. Missing critical baseline or follow-up data relevant to study endpoints.

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Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm in the spinal cord palsy Spinal Cord Compression spinal cord neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Metastatic spinal tumors Neurological deficits Paralysis Spinal cord compression

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.