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Soy food may lower heart attack risk in women, large study suggests

NCT ID NCT00241735

Prevention Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This large observational study followed over 135,000 Chinese women aged 40-70 to see if eating soy food reduces the risk of heart attacks and fatal heart disease. Researchers tracked participants' soy intake and heart health over time. The study aims to provide clues about diet and heart disease prevention, but because it is observational, it cannot prove that soy alone causes any risk reduction.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
soy food
What this could lead to
If soy food is linked to lower heart disease risk, it could support dietary recommendations for heart health in women.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Other lifestyle factors may explain any link seen.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

135,896 people

The number who actually took part.

Start date

Sep 2005

Finished

May 2009

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The Shanghai Women's Health Study (SWHS) Cohort

Ages

40 to 70 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

All women 40-70 years of age and living in the study communities

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder Coronary Disease heart disorder coronary artery disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiovascular diseases Coronary disease Heart diseases

More trials for these conditions

Other studies related to the condition(s) this trial covers.