Could half the steroid dose protect preterm babies just as well?

NCT ID NCT05114096

Recruiting now Disease control Sponsor: McMaster University Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 22, 2026 · Updated 31 times

Summary

This study looks at whether giving pregnant people half the usual dose of a steroid (Celestone) can prevent serious health problems in babies born early. About 3,254 participants will be randomly assigned to receive either the standard two doses or just one dose. The goal is to see if the lower dose works just as well to keep babies safe from breathing issues, brain bleeds, and other complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

(CIUSSS de l'Estrie-CHUS); Université de Sherbrooke
RECRUITING

Sherbrooke, Quebec, Canada
Alberta Health Services; University of Alberta
RECRUITING

Edmonton, Alberta, Canada
Dalhousie University; Izaak Walton Killam Health
RECRUITING

Halifax, Nova Scotia, Canada
Dr. Everett Chalmers Regional Hospital
RECRUITING

Fredericton, New Brunswick, Canada
Fraser Health, University of British Columbia; Jim Pattison Outpatient Care and Surgery Centre
NOT_YET_RECRUITING

Surrey, British Columbia, Canada
Hopital Maisonneuve Rosemont, CIUSSS de l'est de l'Ile de Montréal
RECRUITING

Montreal, Quebec, H1T 2M4, Canada
McGill University, McGill University Health Center, Royal Victoria Hospital
RECRUITING

Montreal, Quebec, Canada
McMaster University
RECRUITING

Hamilton, Ontario, Canada
Memorial University, Eastern Health
NOT_YET_RECRUITING

St. John's, Newfoundland and Labrador, Canada
Mount Sinai Hospital
RECRUITING

Toronto, Ontario, Canada
Queen's University, Kingston General Hospital Health Sciences Centre
RECRUITING

Kingston, Ontario, Canada
Royal Columbian Hospital
NOT_YET_RECRUITING

New Westminster, British Columbia, Canada
Sir Mortimer B. Davis Jewish General Hospital; McGill University
NOT_YET_RECRUITING

Montreal, Quebec, Canada
Sunnybrook Health Sciences Center
RECRUITING

Toronto, Ontario, Canada
The Centre Hospitalier Universitaire Sainte-Justine, Université de Montréal
RECRUITING

Montreal, Quebec, Canada
The Moncton Hospital, Horizon Health Network
RECRUITING

Moncton, New Brunswick, Canada
University of British Columbia; BC Women's Hospital
NOT_YET_RECRUITING

Vancouver, British Columbia, Canada
University of Calgary, Cumming School of Medicine
RECRUITING

Calgary, Alberta, Canada
University of Manitoba, Health Sciences Centre
NOT_YET_RECRUITING

Winnipeg, Manitoba, Canada
University of Manitoba; St. Boniface General Hospital
NOT_YET_RECRUITING

Winnipeg, Manitoba, Canada
University of Ottawa; The Ottawa Hospital
RECRUITING

Ottawa, Ontario, Canada
University of Saskatchewan, Regina General Hospital
NOT_YET_RECRUITING

Saskatoon, Saskatchewan, Canada
Université Laval, Centre de recherche du CHU de Québec
RECRUITING

Québec, Quebec, Canada
Victoria General Hospital
NOT_YET_RECRUITING

Victoria, British Columbia, Canada
Western University; London Health Sciences Centre, Victoria Hospital
RECRUITING

London, Ontario, Canada

Conditions

Explore the condition pages connected to this study.

COMPLICATION OF PREMATURITY OBSTETRIC LABOR, PREMATURE OBSTETRIC LABOR, PREMATURE PREGNANCY COMPLICATIONS PREGNANCY COMPLICATIONS PREMATURE BIRTH PREMATURE BIRTH PRETERM BIRTH