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Bright light, better nights: new hope for veterans with TBI

NCT ID NCT03785600

Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether sitting in front of a bright lightbox for an hour each morning could improve sleep, reduce pain, and boost quality of life in 77 veterans with chronic mild traumatic brain injury (mTBI). Participants used either a lightbox or a negative ion generator (placebo) for 60 minutes within 90 minutes of waking. The goal was to see if better sleep could help veterans recover more fully from their injuries.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Morning bright light therapy (lightbox)
What this could lead to
If effective, this could offer a simple, low-cost way to improve sleep and reduce pain in veterans with TBI, helping them recover better.
What could go wrong
This was a small, completed trial with only 77 participants, so results may not apply to all veterans. Light therapy may not work for everyone and can cause eye strain or headache.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

77 people

The number who actually took part.

Started

Nov 2019

Finished

Sep 2024

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Veteran * Medical record-confirmed diagnosis of mTBI * Current self-reported sleep-wake disturbances * defined by clinically abnormal Insomnia Severity Index and/or Functional Outcomes of Sleep scores * Moderate to severe pain * defined as a score of 4 on an 11-point scale94) persisting for longer than 6 months * English speaking with phone access Exclusion Criteria: Exclusion Criteria: * Decisional impairment and/or dementia * Current usage of a lightbox or negative ion generator * Shift work * History of macular degeneration and/or bipolar disorder * Evidence for suicidal ideation * Cancer diagnosis within the past 6 months * Surgery within the past 6-12 months * Substance abuse within the past 6-12 months

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic Chronic Pain traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Traumatic brain injury

Contacts and locations

Locations

  • VA Portland Health Care System, Portland, OR

    Portland, Oregon, 97207-2964, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.