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Could a Patient's own blood help build better jawbone for dental implants?

NCT ID NCT07677007

Disease control Sponsor: Gulf Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This trial tests whether adding a concentrate made from a patient's own blood (L-PRF) to a standard bone graft improves bone growth for dental implants in the upper jaw. The study includes 30 adults with low bone height in the back of the upper jaw who need implants. Half will receive the standard bone graft alone, and half will get the standard graft plus the L-PRF block. Researchers will measure bone gain and new bone formation after six months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Deproteinized bovine bone mineral (xenograft) and leukocyte- and platelet-rich fibrin (L-PRF) block
What this could lead to
If adding L-PRF to the bone graft works better, it could speed up healing and improve bone quality for people needing dental implants in the upper jaw.
What could go wrong
This is a small, early-stage trial with only 30 participants, so results may not apply to everyone. The L-PRF combination might not show a clear benefit over the standard graft alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 21 years or older. * Partially edentulous posterior maxilla requiring implant-supported rehabilitation. * Residual bone height between 2 and 5 mm measured by CBCT. * Good oral hygiene and compliance with maintenance visits. * ASA I or II patients. * Signed informed consent. Exclusion Criteria: * Uncontrolled systemic diseases. * Smoking more than 10 cigarettes/day. * Active sinus pathology or chronic sinusitis. * Previous sinus augmentation surgery. * Pregnancy or lactation. * Bisphosphonate therapy. * Immunocompromised patients. * History of head and neck radiotherapy

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Maxillary sinus floor elevation Sinus floor augmentation Sinus lift Xenograft

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Gulf Medical University

    RECRUITING

    Ajman, Ajman Emirate, 00000, United Arab Emirates

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