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Could a silver solution soothe Kids' tooth pain?

NCT ID NCT06165042

Symptom relief Sponsor: Marmara University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a liquid called silver diamine fluoride on children's molars that are extra sensitive due to a condition called molar-incisor hypomineralisation. The goal was to see if it could reduce pain and help with chewing. Thirty-four children aged 8 to 13 took part, and the researchers checked how well the treatment worked using standard dental exams.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
silver diamine fluoride
What this could lead to
If it works, this could offer a simple, non-drilling way to reduce tooth sensitivity and improve chewing in children with this condition.
What could go wrong
This was a small, completed study with only 34 children, so results may not apply to everyone. The treatment is for symptom relief, not a cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

34 people

The number who actually took part.

Started

Apr 2024

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

8 to 13 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Children aged between 8 and 13 who are cooperative, having at least 2 teeth with a BAKH-TII score of 4a or 4b. * Complete occlusion of teeth with MIH. * Presence of signs of pulpal pathology with symptoms in the teeth included in the study during the pre-treatment clinical examination (absence of spontaneous and prolonged pain, no percussion and palpation sensitivity, no swelling or fistula in soft tissue, presence of periapical radiolucency in radiographs, and absence of internal or external resorption). * Additionally, no parafunctional habits (e.g., bruxism) and no malocclusion (posterior crossbite). * Good general health condition, without systemic illnesses. * Absence of silver allergy. Exclusion Criteria: * Non-cooperative individuals. * Having MIH severity outside the specified scoring. * Presence of systemic diseases. * Lack of complete occlusion in the molars. * Presence of parafunctional habits. * Presence of pulpal pathology. * Individuals with a silver allergy.

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Conditions

The condition(s) this trial relates to.

Molar Hypomineralization

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Molar incisor hypomineralisation

Contacts and locations

Locations

  • Marmara University

    Istanbul, 34854, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.