Shorter antibiotic course may be just as effective for tough lung infections
NCT ID NCT03477292
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a 7-day course of antibiotics works as well as the standard 14-day course for treating a serious lung infection (ventilator-associated pneumonia) caused by drug-resistant bacteria. The goal was to see if shorter treatment could reduce side effects and help prevent antibiotic resistance. The study involved 41 adults on ventilators who had this specific infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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41 people
The number who actually took part.
- Started
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Mar 2018
- Finished
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Dec 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: (a) Patients who develop ventilator associated pneumonia due to drug-resistant Acinetobacter baumanii; (b) age group of 18 to 75 years Exclusion Criteria: (a) VAP due to other organisms; (b) pregnancy; (c) endotracheal or tracheostomy tube aspirate demonstrating growth of drug sensitive Acinetobacter baumanii or an organism other than Acinetobacter baumanii; and, (c) failure to provide informed consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Respiratory ICU, Department of Pulmonary Medicine, PGIMER
Chandigarh, Chandigarh, 160012, India
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Respiratory ICU, Post Graduate Institue of Medical Education and Research
Chandigarh, Chandigarh, 160012, India
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Fast lung test may help doctors pick the right antibiotic sooner
- Rethinking staff training to fight a deadly ICU infection
- Speedier lab test could curb superbug threat in ICU pneumonia
- Human milk mouth care may shield preemies from lung infections
- Could a 'robotic cough' stop deadly pneumonia in ICU patients?