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Could two weeks of radiation be enough for breast cancer?

NCT ID NCT04175210

First seen May 23, 2026 · Last updated Jun 23, 2026 · Updated 4 times

Summary

This phase 3 trial compares a standard 3-week radiation course to an experimental 2-week course for women with early-stage breast cancer. About 400 participants who had lumpectomy will receive whole breast radiation plus an extra boost to the tumor site. The study checks if the shorter schedule causes similar side effects and controls cancer just as well.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brooklyn Methodist Hospital - NewYork Presbyterian

    New York, New York, 11215, United States

  • New York Presbyterian Hospital - Queens

    New York, New York, 11355, United States

  • New York Presbyterian Hospital at Lower Manhattan Cancer Center

    New York, New York, 10007, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy

What this could lead to

If successful, this could offer a shorter, more convenient radiation schedule for early breast cancer patients without compromising outcomes.

What could go wrong

This is a non-inferiority trial, so it aims to show the shorter course is not worse, not better. Results may not apply to all breast cancer types or stages.

Conditions

The condition(s) this trial relates to.

breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.