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Sepsis heart damage: new study aims to unravel mysteries

NCT ID NCT04695119

Knowledge-focused Sponsor: Linkoeping University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how sepsis, a severe infection, can cause heart problems in intensive care patients. Researchers will collect data, blood samples, and heart ultrasound images from 330 adults with septic shock. The goal is to find patterns that help doctors better diagnose and predict heart complications from sepsis.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better tools for diagnosing and predicting heart problems in sepsis patients, potentially improving care.
What could go wrong
This is an observational study, not testing a new treatment. It may not directly change patient outcomes, and results may not apply to all sepsis patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

379 people

The number who actually took part.

Started

Sep 2018

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All consecutive patients admitted to participating ICUs with a presumptive diagnosis of septic shock will be screened for eligibility. Patients fulfilling the Sepsis-III criteria for septic shock will included. Study inclusion must occur within 12h of ICU admission.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients admitted to ICU and fulfilling the Sepsis-III criteria for septic shock Exclusion Criteria: * No informed consent * Acute coronary syndromes

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Conditions

The condition(s) this trial relates to.

cardiomyopathy infectious disease with sepsis multiple organ dysfunction syndrome Sepsis toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiomyopathies Organ failure, multiple Sepsis Septic shock

Contacts and locations

Locations

  • CHU Dijon-Bourgogne

    Dijon, 21000, France

  • CHU Georges Pompidou

    Paris, 75015, France

  • Dept of Anaesthesia and Intensive Care

    Linköping, 58185, Sweden

  • Ryhov Sjukhus Jönköping

    Jönköping, 55305, Sweden

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