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New cocktail targets Hard-to-Treat myeloma in 33-Patient trial

NCT ID NCT05530421

First seen Feb 27, 2026 · Last updated Apr 28, 2026 · Updated 9 times

Summary

This study tests whether a combination of three drugs (selinexor, venetoclax, and dexamethasone) can shrink tumors in people with a specific genetic subtype of multiple myeloma (t(11;14)) that has returned or stopped responding to prior treatments. About 33 adults will receive the drug combo, and doctors will measure how many achieve a partial or complete response. The goal is to control the disease, not cure it, as ongoing management is still needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • University of Miami, Lennar Foundation Medical Center

    RECRUITING

    Coral Gables, Florida, 33146, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Miami, Sylvester Comprehensive Cancer Center

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • University of Miami, Sylvester Comprehensive Cancer Center at Deerfield Beach

    RECRUITING

    Deerfield Beach, Florida, 33442, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.