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Bladder cancer combo trial halted early after just 4 patients

NCT ID NCT04856189

First seen Feb 01, 2026 · Last updated May 23, 2026 · Updated 14 times

Summary

This study tested a combination of two drugs, selinexor and pembrolizumab, for people with advanced bladder cancer who either could not take the standard chemotherapy cisplatin or whose cancer had worsened after cisplatin. The goal was to find the best dose and see if the combination could shrink tumors. However, the trial was stopped early after enrolling only 4 participants, so no strong conclusions can be drawn about its effectiveness.

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Contacts and locations

Locations

  • University of California Davis Comprehensive Cancer Center

    Sacramento, California, 95817, United States

Conditions

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