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New combo therapy shows promise for older AML patients

NCT ID NCT02835222

First seen Jan 04, 2026 · Last updated May 23, 2026 · Updated 19 times

Summary

This study tests whether adding the drug selinexor to standard chemotherapy can help older adults with untreated acute myeloid leukemia (AML) live longer and achieve remission. About 57 participants will receive either standard chemo alone or chemo plus selinexor, followed by maintenance therapy. The goal is to see if the combination improves survival and reduces cancer more effectively.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Comprehensive Cancer Center of Wake Forest University

    Winston-Salem, North Carolina, 27157, United States

  • Virginia Commonwealth University Massey Cancer Center

    Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.