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Hookah haze: secondhand smoke may stiffen arteries in non-smokers

NCT ID NCT04661683

Knowledge-focused Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how breathing in secondhand hookah smoke or e-hookah vapor affects blood vessel health. Healthy non-smokers aged 21-49 will have their blood flow and artery stiffness measured before and after brief exposure to hookah smoke, e-hookah aerosol, or clean air. The goal is to understand the short-term risks to people who don't smoke but are around hookah use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 12 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2021

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 49 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 21-49 years old * Never a smoker: do not use any tobacco products or nicotine delivery systems, including cigarettes, cigars (traditional and filtered), cigarillos, hookah, smokeless tobacco (i.e., loose snus, moist snuff, dip, spit, or chewing tobacco), pipe tobacco, snus pouches, dissolvable tobacco or vaping. * no evidence of cardiopulmonary disease by history/physical * blood pressure (BP) \< 140/90 mmHg * resting heart rate (HR) \< 100 bpm * BMI \>18 or \< 30kg•m2 * no prescription medication * No exposure to environmental tobacco smoke for at least one week prior to the study date. Exclusion Criteria: * exhaled carbon monoxide \>6 ppm * (+) pregnancy test * other conditions deemed unsafe to participate, such as breastfeeding

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Conditions

The condition(s) this trial relates to.

Vaping Water Pipe Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hookah smoking Secondhand aerosol VAPING Vascular stiffness

Contacts and locations

Locations

  • University of California, Los Angeles

    Los Angeles, California, 90095-8361, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.