New drug aims to tame rare blood sugar disorder in kids and adults
NCT ID NCT06208215
First seen Jan 09, 2026 · Last updated May 22, 2026 · Updated 18 times
Summary
This study tests an investigational drug called RZ358 for people with congenital hyperinsulinism, a rare condition causing dangerously low blood sugar. About 56 participants aged 3 months to 45 years who haven't responded well to standard treatments will receive either RZ358 or a placebo for 24 weeks. The goal is to see if RZ358 can reduce low blood sugar episodes and improve safety.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Cook Children's Medical Center
Fort Worth, Texas, 76104, United States
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Rezolute Investigative Site, Al Rayyan, Qatar
Al Rayyan, Qatar
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Rezolute Investigative Site, Ankara, Turkey
Ankara, 06800, Turkey (Türkiye)
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Rezolute Investigative Site, Athens, Greece
Athens, 115 27, Greece
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Rezolute Investigative Site, Barcelona, Spain
Barcelona, 08035, Spain
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Rezolute Investigative Site, Berlin, Germany
Berlin, 13353, Germany
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Rezolute Investigative Site, Bron, France
Bron, 69677, France
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Rezolute Investigative Site, Dusseldorf, Germany
Düsseldorf, 40225, Germany
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Rezolute Investigative Site, Hà Nội, Vietnam
Hà Nội, 100000, Vietnam
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Rezolute Investigative Site, London, United Kingdom
London, WC1N 3JH, United Kingdom
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Rezolute Investigative Site, Manchester, United Kingdom
Manchester, M13 9WL, United Kingdom
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Rezolute Investigative Site, Odense, Denmark
Odense, 5000, Denmark
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Rezolute Investigative Site, Paris, France
Paris, 75015, France
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Rezolute Investigative Site, Seeb, Oman
Seeb, 123, Oman
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Rezolute Investigative Site, Sevilla, Spain
Seville, 41013, Spain
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Rezolute Investigative Site, Tbilisi, Georgia
Tbilisi, 0159, Georgia
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Rezolute Investigative Site, Varna, Bulgaria
Varna, 9010, Bulgaria
Conditions
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