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New drug hope for kids with lung damage after transplant

NCT ID NCT04908735

First seen Jan 08, 2026 · Last updated May 23, 2026 · Updated 24 times

Summary

This study tested the drug ruxolitinib for children and adults who develop early lung problems after a stem cell transplant. Lung issues like bronchiolitis obliterans are common and often found too late. The goal was to see if adding ruxolitinib to standard treatment could reverse lung injury and prevent long-term damage. The study was stopped early after enrolling only 7 participants.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

Conditions

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