New drug hope for Kids' lung damage after transplant

NCT ID NCT04908735

First seen Jan 08, 2026 · Last updated May 14, 2026 · Updated 20 times

Summary

This study tested the drug ruxolitinib for children and adults who developed early lung problems after a stem cell transplant. Lung issues like bronchiolitis obliterans (BO) can be serious and are often found too late. The goal was to see if adding ruxolitinib to standard treatment could reverse lung damage and prevent long-term breathing problems. The study was stopped early after enrolling only 7 participants.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.