New drug hope for lung damage after transplant falls short

NCT ID NCT04908735

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested the drug ruxolitinib to treat early lung damage in children and adults who had a stem cell transplant. Lung problems like bronchiolitis obliterans can be serious and hard to detect early. The trial aimed to see if adding ruxolitinib to standard care could improve lung function. Only 7 people enrolled before the study was stopped early.

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Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans bronchiolitis obliterans syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States