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New dental filler shows promise in retreating infected root canals

NCT ID NCT05714384

Disease control Sponsor: Ministry of Health, Kuwait Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how well a special dental material (calcium silicate sealer) works when re-treating root canals that have failed. 136 adults aged 18-65 with infected teeth were included. The main goal was to see if the infection healed on 3D X-rays and if symptoms like pain or swelling went away.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

136 people

The number who actually took part.

Started

Mar 2023

Finished

Dec 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who present with symptomatic teeth and require root canal retreatment will be assessed based on inclusion and exclusion criteria.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants must be 18-65 years of age at the time of recruitment * Participants must have a classification of I or II on the American Society of Anesthesiologists (ASA) physical status classification system * Participants must not have known allergies to any materials used in the study * Participants must agree to participate in the study by signing a consent form * Participants must have good oral hygiene * All types of permanent teeth that require root canal retreatment are included (incisors, canines, premolars \& molars) * The teeth must be restorable and have fully formed roots with no advanced periodontal disease Exclusion Criteria: * ASA classification of III or more * Pregnant or breastfeeding women * Patients who are unable to give consent * Patients who have advanced periodontal disease or teeth with more than 5mm probing * Teeth with incomplete root formation * Teeth that have a poor restorative prognosis * Teeth presenting with signs of a vertical root fracture * Teeth with blocked or non-negotiable canals * Teeth with broken instruments * Teeth with iatrogenic perforations * Teeth requiring posts or extensive prosthetic rehabilitation * Teeth with cracks * Teeth with internal or external root resorption * Teeth with uncontrollable exudate

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Conditions

The condition(s) this trial relates to.

dental abscess Periapical Diseases suppurative periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periapical diseases Root canal infection

Contacts and locations

Locations

  • Jaber Al-Ahmed Dental Center

    Janūb as Surrah, Hawalli Governate, 00000, Kuwait

More trials for these conditions

Other studies related to the condition(s) this trial covers.