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Chilled or heated rinses may ease root canal pain, study finds

NCT ID NCT07191990

Symptom relief Sponsor: Future University in Egypt Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether using cold, hot, or ultrasound-activated rinsing solutions can lower pain and bacteria after a root canal. Sixty adults with painful tooth pulp inflammation will receive one of four rinsing methods. The goal is to find which approach works best for a more comfortable recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with age range between 18 to 40. * No sex predilection. * Patients with symptomatic irreversible pulpitis. * Patients able to sign informed consent. * Restorable teeth * Positive patient's acceptance for participating in the study. * Type III distal and mesial canal of first mandibular molar. * Mild to moderate (5-20) ° curvature according to Schneider Exclusion Criteria: * Pregnant females * Medically compromised patients. * Patients having analgesics before the treatment * If antibiotic have been administrated during the past two weeks preoperatively. * Patients having bruxism or clenching * Patients having sever malocclusion associated with traumatic occlusion. * Teeth that have: Peri-apical periodontitis Root resorption Pain on percussion Pulp stones or calcifications Previous endodontic treatment. -Non-patent canals

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Symptomatic irreversible pulpitis (SIP)

Contacts and locations

Locations

  • Future University in Egypt

    Cairo, New Cairo, 11835, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.