Can a simple wash save a tooth that hurts?
NCT ID NCT07748676
First seen Aug 06, 2026 · Last updated Aug 27, 2026 · Updated 3 times
Summary
This trial tests whether using calcium hypochlorite or sodium hypochlorite to clean the pulp wound during a partial pulpotomy can improve the success of saving painful, deeply decayed permanent molars. Adults aged 18-40 with symptomatic irreversible pulpitis will undergo the procedure, and the study will compare tooth survival, pain, and quality of life over 12 months. The goal is to find a better way to preserve natural teeth and avoid more invasive treatments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Partial pulpotomy procedure using calcium hypochlorite or sodium hypochlorite as wound lavage agents
- What this could lead to
- If successful, this could establish a better way to preserve painful, deeply decayed molars and avoid root canal treatment or tooth loss.
- What could go wrong
- This is a small, early-stage trial, and results may not apply to all cases. The procedure may fail, leading to persistent pain or the need for further treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 106 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. patients aged 18-40 years 2. Mature permanent mandibular molars with extremely deep caries (caries penetrating the entire thickness of the dentine radiographically, without radiopaque zone separating lesion from the pulp) and clinical diagnosis of SIP with PAI score ≤ 2 3. Periodontally healthy teeth (probing pocket depth ≤3 mm and mobility within normal limit) 4. Patients having physical status of class 1 or 2 according to ASA classification 5. Pulpal bleeding could be controlled within 10 min following pulp amputation Exclusion Criteria: 1. Non restorable teeth 2. No pulp exposure even after complete caries excavation 3. Necrotic or partially necrotic pulp upon exposure 4. Presence of sinus tract or soft tissue swelling 5. Radiographic signs of internal or external root resorption 6. Pregnant women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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PGIDS
RECRUITINGRohtak, Haryana, 124001, India
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