Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Warm-Up for kidneys: could a machine bath boost transplant success?

NCT ID NCT05782543

Disease control Sponsor: University Medical Center Groningen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether giving a donor kidney a 4-6 hour warm bath on a machine (normothermic machine perfusion) right before transplant helps it work better a year later. The trial includes 240 adults receiving a kidney from a donor aged 50 or older. Half get the standard cold storage, half get the extra warm perfusion.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Normothermic machine perfusion (a procedure that warms and pumps the kidney before transplant)
What this could lead to
If it works, this could improve kidney function after transplant and reduce complications like delayed graft function.
What could go wrong
This is a mid-stage trial with 240 participants, so results may not apply to all patients. The procedure adds time and complexity, and benefits are not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 240 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2024

Expected to finish

May 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 100 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients receiving their first or second kidney transplant; * Patients receiving a graft from a ≥ 50-year-old donor; * Patients receiving a graft from a DCD or DBD donor; * Patients receiving a kidney transplant in the UMCG, the Erasmus MC, or the LUMC; * Patients receiving a graft stored on HMP; * Patients ≥ 18 years of age; * Patients having provided written informed consent. Exclusion Criteria: * Patients receiving their third or subsequent kidney transplant; * Patients receiving a graft from a donor \< 50 years; * Patients receiving a graft not stored on HMP; * Patients receiving a graft from a donor that underwent normothermic regional perfusion (NRP); * Patients receiving a kidney transplant in another center than the UMCG, Erasmus MC, or LUMC; * Patients receiving a multi-organ transplantation; * Patients receiving a kidney with complex arterial anatomy (3 or more arteries); * Recipients \< 18 years of age.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for End-stage renal disease are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Kidney transplant; complications

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Erasmus Medical Center

    RECRUITING

    Rotterdam, Netherlands

  • Leiden University Medical Center

    NOT_YET_RECRUITING

    Leiden, Netherlands

  • University Medical Center Groningen

    RECRUITING

    Groningen, Provincie Groningen, Netherlands

More trials for these conditions

Other studies related to the condition(s) this trial covers.