New hope for kids with relapsed leukemia: experimental drug combo enters safety trial
NCT ID NCT06177067
First seen Nov 03, 2025 · Last updated Apr 30, 2026 · Updated 26 times
Summary
This early-stage study tests whether adding a new drug called revumenib to two standard chemotherapy drugs is safe for children and young adults whose acute myeloid leukemia (AML) has not responded to treatment or has returned. About 24 participants will receive the three-drug combination to find the safest dose and see if it can lead to remission. The goal is to control the disease, not to cure it, as ongoing management may still be needed.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Children's Healthcare of Atlanta
RECRUITINGAtlanta, Georgia, 30329, United States
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Children's Hospital Colorado
RECRUITINGAurora, Colorado, 80045, United States
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Children's Mercy Hospital of Kansas City
RECRUITINGKansas City, Missouri, 64108, United States
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Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229, United States
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Cook Children's Medical Center
RECRUITINGFort Worth, Texas, 76104, United States
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Memorial Sloan- Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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Rady Children's Hospital
RECRUITINGSan Diego, California, 92132, United States
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St. Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 38105, United States
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UT Southwestern/Simmons Cancer Center
RECRUITINGDallas, Texas, 75390, United States
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Conditions
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