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Retinaldehyde cream shows promise for smoother, firmer skin

NCT ID NCT07510165

Symptom relief Sponsor: Medical University of Silesia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a retinaldehyde cream (a form of vitamin A) can improve signs of aging skin in women aged 30 to 60. Fifty-six women applied a stronger cream (0.1%) to one side of their face and a weaker cream (0.05%) to the other side every evening for 24 weeks. Researchers measured skin hydration, oiliness, firmness, wrinkles, and color at the start, after 12 weeks, and after 24 weeks to see if the creams made a difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

56 people

The number who actually took part.

Started

Feb 2023

Finished

Jul 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 60 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 30-60 years * Presence of wrinkles, dark spots, acne, seborrhea * Decreased skin firmness Exclusion Criteria: * Exacerbated active atopic dermatitis on the face * Pregnancy * Skin infections * Numerous erosions or excoriations on facial skin * No aesthetic medical treatments within the preceding 6 months * Administration of botulinum toxin within the preceding 3 months * Irritated, dry skin * Irritated or excessively dry skin

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Photoaging Skin aging

Contacts and locations

Locations

  • Department of Basic Biomedical Science, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Sosnowiec, Poland

    Sosnowiec, 41-205, Poland

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