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Could a red wine compound beat plaque? new trial tests resveratrol mouthwash

NCT ID NCT07393802

Disease control Sponsor: University of Baghdad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a mouthwash made from resveratrol (a compound found in grapes) can reduce dental plaque buildup. Twenty healthy adults will rinse with the resveratrol mouthwash, a standard chlorhexidine mouthwash, or a placebo, and then avoid brushing for 24 hours to see how much plaque forms. The goal is to find a gentler alternative to chlorhexidine, which can cause side effects like staining.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Resveratrol-based mouthwash (Oroxil®)
What this could lead to
If it works, this could point toward a natural alternative to chlorhexidine mouthwash for controlling dental plaque.
What could go wrong
This is a small, early-phase trial with only 20 healthy participants, so results may not apply to the general population. The effect is measured over just 24 hours, so long-term benefits or risks are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 25 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 30 years * Systemically healthy individuals * Presence of at least 20 natural teeth * Clinically healthy gingiva with no signs of gingivitis or periodontitis * No probing depth \>3 mm * No clinical attachment loss Exclusion Criteria: * Presence of gingivitis or periodontitis * Active dental caries requiring treatment * History of periodontal therapy within the previous 6 months * Use of antibiotics, anti-inflammatory drugs, or antiseptic mouthwashes within the previous 3 months * Smoking or tobacco use * Pregnancy or lactation * Known allergy to any mouthwash components

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Biofilm formation Chlorhexidine Mouthwash Periodontal health

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ahmed Hashim

    Karbala, Iraq

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