Could a red wine compound beat plaque? new trial tests resveratrol mouthwash

NCT ID NCT07393802

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a mouthwash made from resveratrol (a compound found in grapes) can reduce dental plaque buildup. Twenty healthy adults will rinse with the resveratrol mouthwash, a standard chlorhexidine mouthwash, or a placebo, and then avoid brushing for 24 hours to see how much plaque forms. The goal is to find a gentler alternative to chlorhexidine, which can cause side effects like staining.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Resveratrol-based mouthwash (Oroxil®)

What this could lead to

If it works, this could point toward a natural alternative to chlorhexidine mouthwash for controlling dental plaque.

What could go wrong

This is a small, early-phase trial with only 20 healthy participants, so results may not apply to the general population. The effect is measured over just 24 hours, so long-term benefits or risks are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ahmed Hashim

    Karbala, Iraq

    Contact Phone: •••-•••-•••• Email: •••••@•••••