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Red wine compound tested for knee pain relief in major trial

NCT ID NCT02905799

Symptom relief Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether resveratrol, a natural substance found in grapes and red wine, can reduce pain in people with knee osteoarthritis. 142 adults with painful knee arthritis took either resveratrol or a placebo pill daily for three months. The main goal was to measure changes in knee pain using a simple 0-100 scale.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

142 people

The number who actually took part.

Started

Nov 2017

Finished

May 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 40 years-old * Knee osteoarthritis fulfilling 1986 American College of Rheumatology (ACR) criteria * Pain on numeric rating scale ≥ 40/100 * Symptom duration ≥ 1 month * Kellgren and Lawrence X-Ray score 1, 2 or 3 * Written consent obtained * Health insurance cover Exclusion Criteria: * History of symptomatic crystal or inflammatory arthritis * Knee surgery ≤ 1 year * Knee trauma ≤ 2 months * Knee intra-articular injections of corticosteroids and/or hyaluronic acid ≤ 2 months * Neurologic disorders involving the lower limbs * Patient not understanding and not speaking french * Participation in another biomedical research * Contraindication to resveratrol or hypersensitivity to any of its constituents * Current use of intramuscular, intravenous or oral corticosteroids * Uncontrolled diseases that may require intramuscular, intravenous or oral corticosteroids * Current use of anticoagulants

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthritis

Contacts and locations

Locations

  • Rehabilitation Department, Cochin Hospital

    Paris, Paris, 75014, France

  • Rehabilitation department , CHU Clermont-Ferrand

    Cébazat, 63118, France

  • Rheumatology Department, Saint Antoine Hospital

    Paris, Paris, 75012, France

More trials for these conditions

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